9/16/2023 0 Comments Calnexin and calreticulin![]() Calreticulin is located in storage compartments associated with the endoplasmic reticulum and is considered an ER resident protein. The Ca 2+ is bound with low affinity, but high capacity, and can be released on a signal (see inositol trisphosphate). Ĭalreticulin is a multifunctional soluble protein that binds Ca 2+ ions (a second messenger in signal transduction), rendering it inactive. negative regulation of trophoblast cell migrationĬalreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 ( ERp60) is a protein that in humans is encoded by the CALR gene.positive regulation of endothelial cell migration.vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane.antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent.positive regulation of NIK/NF-kappaB signaling.glucocorticoid receptor signaling pathway.positive regulation of cell population proliferation.positive regulation of substrate adhesion-dependent cell spreading.ATF6-mediated unfolded protein response.cortical actin cytoskeleton organization.negative regulation of transcription, DNA-templated.negative regulation of transcription by RNA polymerase II.antigen processing and presentation of peptide antigen via MHC class I.peptide antigen assembly with MHC class I protein complex.negative regulation of retinoic acid receptor signaling pathway.regulation of transcription, DNA-templated.negative regulation of intracellular steroid hormone receptor signaling pathway.positive regulation of dendritic cell chemotaxis.protein folding in endoplasmic reticulum.negative regulation of neuron differentiation. ![]()
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